About James Mosley


Dr. Mosley is a board-certified, fellowship- trained physician with outstanding skills in treating cancer and blood diseases. He successfully manages patients with complex health issues and provides compassionate, exceptional care. Dr. Mosley also serves as Director of Hematology and Oncology Clinical Trials. He is a prolific author, serving as lead author on numerous clinical publications. Dr. Mosley is a sought after presenter at professional conferences and is highly respected by his peers and patients.




Hematology, Hematology Oncology, Internal Medicine, Medical Oncology





  • Hematology
  • Internal Medicine
  • Medical Oncology


  • 1999, The University Of Tennessee, Knoxville, BS
  • 2003, University of Tennessee College of Medicine, MD


  • 2006, Barnes-Jewish Hospital, Department of Medicine


  • 2009, Washington University, Department of Medicine

Professional Affiliations

  • American Society of Clinical Oncology, Active Member
  • Missouri Medical Society, Active Member
  • Cape Girardeau Area Medical Society, Active Member

Office Locations

Southeast Cancer Center

789 South Mount Auburn Road
Cape Girardeau, MO 63703    Maps & Directions
Phone: 573-519-4830


Dr. James Mosley, an oncologist at Southeast Cancer Center, talks with us about the causes and diagnosis of breast cancer.

James Mosley III, MD, Hematologist/Oncologist at Southeast Cancer Center in Cape Girardeau, Missouri.

Areas of Expertise

  • Cancer and Blood Diseases
  • Congenital Bleeding & Clotting Disorders
  • Supportive and Palliative care in Cancer & Blood Diseases


  • Knowlton Incentive for Excellence Award, Barnes-Jewish Hospital and Barnes- Jewish Foundation, Department of Internal Medicine, 2007
  • Summa Cum Laude, University of Tennessee
  • Most Outstanding Senior, Department of Microbiology, 1999
  • Threshold Honors Scholar, 1997-1999: Honors program at the University of Tennessee providing a research-oriented biology curriculum with extensive hands-on research experience to competitively selected undergraduate students.

Publications & Research

  • Chawla JS, Ghobadi A, Mosley J 3rd, Verkruyse L, Trinkaus K, Abboud CN, Cashen AF, Stockerl-Goldstein KE, Uy GL, Westervelt P, Dipersio JF, Vij R.  Oral valganciclovir versus ganciclovir as delayed pre-emptive therapy for patients after allogeneic hematopoietic stem cell transplant: a pilot trial (04-0274) and review of the literature. Transpl Infect Dis. 2012 Jun;14(3):259-67.
  • Vij R, Ansstas G, Mosley JC, Bryant G, Hassan A, Amador-Ortiz C, Procknow E.  Efficacy and tolerability of PTK787/ZK 222584 in a phase II study of post-transplant maintenance therapy in patients with multiple myeloma following high-dose chemotherapy and autologous stem cell transplant.  Leuk Lymphoma. 2010 Aug;51(8):1577-9.
  • Mosley JC, Stokerl-Goldstein K. Chronic Leukemias.  In: Govindan R ed.Mosley JC, et al.  Efficacy of cetuximab-based second-line therapy in patients with metastatic head and neck squamous cell carcinoma (HNSCC) which progressed on gefitinib-based first-line therapy.  Poster session, American Society of Clinical Oncology Annual Meeting, 2008.
  • Mosley JC, et al. Tolerability of PTK787/ZK 222584 in a Phase II Study of Post-Transplant Maintenance Therapy in Patients with Multiple Myeloma Following High-Dose Chemotherapy and Autologous Stem Cell Transplant. Abstract, American Society of Hematology Annual Meeting, 2007.
  • Mosley JC, Naughton MN. Kidney Cancer. In: Govindan R ed. The Washington Manual of Oncology. Second Edition. Lippincott, Williams & Wilkins. Philadelphia, 2008.
  • Mosley JC. Transfusion Practices. In: Henderson K ed. The Washington Manual: Hematology and Oncology Subspecialty Consult, 2nd edition. Lippincott, Williams & Wilkins. Philadelphia, 2008.
  • Mosley JC, Faller BA. Urologic and Male Genital Malignancies. In: Henderson K ed. The Washington Manual: Hematology and Oncology Subspecialty Consult. Lippincott, Williams & Wilkins. Philadelphia, 2008.
  • Mosley JC, Blinder M.  Transfusion Practices.  In: Kollef MH ed.  The Washington Manual of Critical Care Medicine.  Lippincott, Williams & Wilkins.  Philadelphia, 2007.
  • Mosley JC.  Hypercoagulable States.  In: Kollef MH ed.  The Washington Manual of Critical Care Medicine.  Lippincott, Williams & Wilkins.  Philadelphia, 2007.
  • Jurado LA, Mosley JC, Jarrett HW.  Cyanogen bromide activation and coupling of ligands to diol-containing silica for high-performance chromatography optimization of conditions.  J. of Chromatography A.  2002 Sept; 971 (1-2): 95-104.