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Akinobu Itoh, MD, PHD

Status Consulting
Medical school Tohoku University School of Medicine , 1998
Medical school Tohoku University School of Medicine, 2010
Fellowship St. Michaels Hospital, 2011
Fellowship Toronto General Hospital, 2012
Residency NTT Medical Center of Tokyo, 2000
General Surgery
Residency NTT Medical Center of Tokyo, 2002
Cardiothoracic Surgery

The Society of Thoracic Surgeons

Special practice interests
  • Heart valve repair/replacement
  • Aortic root surgery
  • Coronary artery bypass (bilateral IMA and off pump surgery)
  • Heart transplantation
  • Mechanical assist device (LVAD/ECMO) for heart failure
  • Pre/post operative patient care
Board certification

Japanese Board of Cardiovascular Surgery


  • The Society for Heart Valve Disease Lillehei Young Investigator Award Finalist (New York, NY)
  • University of Toronto, Department of Surgery , Zane Cohen Clinical Fellow Achievement Award Finalist

Publications & Research

  • Printable elastic conductors by in situ formation of silver nanoparticles from silver flakes. Matsuhisa N, Inoue D, Zalar P, Jin H, Matsuba Y, Itoh A, Yokota T, Hashizume D, Someya T Nat Mater. 2017 May 15; doi: 10.1038/nmat4904.
  • CD137 Plays Both Pathogenic and Protective Roles in Type 1 Diabetes Development in NOD Mice. Forsberg MH, Ciecko AE, Bednar KJ, Itoh A, Kachapati K, Ridgway WM, Chen YG J Immunol. 2017 May 15; 198(10)3857-3868. doi: 10.4049/jimmunol.1601851.
  • Left Ventricular Unloading by Impella Device Versus Surgical Vent During Extracorporeal Life Support. Tepper S, Masood MF, Baltazar Garcia M, Pisani M, Ewald GA, Lasala JM, Bach RG, Singh J, Balsara KR, Itoh A Ann Thorac Surg. 2017 Mar 24; pii: S0003-4975(17)30039-5. doi: 10.1016/j.athoracsur.2016.12.049.
  • Photo-oxidative Cross-Dehydrogenative Coupling-Type Reaction of Thiophenes with α-Position of Carbonyls Using a Catalytic Amount of Molecular Iodine. Sudo Y, Yamaguchi E, Itoh A Org Lett. 2017 Apr 7; 19(7)1610-1613. doi: 10.1021/acs.orglett.7b00428.
  • Cross-Dehydrogenative C-H Amination of Indoles under Aerobic Photo-oxidative Conditions. Yamaguchi T, Yamaguchi E, Itoh A Org Lett. 2017 Mar 17; 19(6)1282-1285. doi: 10.1021/acs.orglett.7b00026.
  • Distribution of glycosylinositol phosphoceramide-specific phospholipase D activity in plants. Kida T, Itoh A, Kimura A, Matsuoka H, Imai H, Kogure K, Tokumura A, Tanaka T J Biochem. 2017 Feb 1; 161(2)187-195. doi: 10.1093/jb/mvw060.
  • Incidence of and risk factors associated with nedaplatin-related hypersensitivity reactions. Kawarada Y, Miyazaki M, Itoh A, Araki R, Iwamizu H, Kataoka T, Kumakura Y, Ota A, Nagai T, Yamada K Int J Clin Oncol. 2017 Jan 25; doi: 10.1007/s10147-017-1091-4.
  • Implantation of left ventricular assist device in a patient with left ventricular non-compaction. Balsara KR, Bierhals A, Vader J, Pasque MK, Itoh A J Card Surg. 2017 Feb; 32(2)159-161. doi: 10.1111/jocs.13088.
  • A Fully Magnetically Levitated Circulatory Pump for Advanced Heart Failure. Mehra MR, Naka Y, Uriel N, Goldstein DJ, Cleveland JC Jr, Colombo PC, Walsh MN, Milano CA, Patel CB, Jorde UP, Pagani FD, Aaronson KD, Dean DA, McCants K, Itoh A, Ewald GA, Horstmanshof D, Long JW, Salerno C, MOMENTUM 3 Investigators. N Engl J Med. 2017 Feb 2; 376(5)440-450. doi: 10.1056/NEJMoa1610426.
  • Direct Determination of Cadmium in Seawater by Standard Addition ICP-QMS/QMS with an ORC. Zhu Y, Itoh A Anal Sci. 2016; 32(12)1301-1305.
  • Induced Expression of Cancer Stem Cell Markers ALDH1A3 and Sox-2 in Hierarchical Reconstitution of Apoptosis-resistant Human Breast Cancer Cells. Kashii-Magaribuchi K, Takeuchi R, Haisa Y, Sakamoto A, Itoh A, Izawa Y, Isa M, Fukuzawa M, Murakami M, Takahashi R Acta Histochem Cytochem. 2016 Nov 1; 49(5)149-158.
  • Distribution of glycosylinositol phosphoceramide-specific phospholipase D activity in plants. Kida T, Itoh A, Kimura A, Matsuoka H, Imai H, Kogure K, Tokumura A, Tanaka T J Biochem. 2016 Nov 8; pii: mvw060.
  • Use of adenosine diphosphate receptor inhibitor prior to left ventricular assist device implantation is not associated with increased bleeding. Tibrewala A, Nassif ME, Andruska A, Shuster JE, Novak E, Vader JM, Ewald GA, LaRue SJ, Silvestry S, Itoh A J Artif Organs. 2017 Mar; 20(1)42-49. doi: 10.1007/s10047-016-0932-7.
  • Advanced hepatocellular carcinoma with hepatic vein tumor thrombosis and renal dysfunction after hepatic arterial infusion chemotherapy effectively treated by liver resection with active veno-venous bypass: report of a case. Itoh A, Sadamori H, Yabushita K, Monden K, Tatsukawa M, Hioki M, Hyodo T, Omonishi K, Ueki T, Ohno S, Sakaguchi K, Takakura N BMC Cancer. 2016 Sep 1; 16705. doi: 10.1186/s12885-016-2749-4.
  • Use of dynamic CT attenuation value for diagnosis of acute gangrenous cholecystitis. Maehira H, Itoh A, Kawasaki M, Ogawa M, Imagawa A, Mizumura N, Okumura S, Kameyama M Am J Emerg Med. 2016 Dec; 34(12)2306-2309. doi: 10.1016/j.ajem.2016.08.033.
  • Extracorporeal left ventricular circulatory support as a bridge to implantable LVAD for a patient with pan-left ventricular thrombosis. Ogawa M, Balsara KR, Masood MF, Itoh A ASAIO J. 2016 Aug 22;
  • Left Ventricular Assist Device Inflow Angle and Pump Positional Change Over Time Adverse Impact on Left Ventricular Assist Device Function. Kazui T, Zhang A, Greenberg J, Itoh A, Tran PL, Keith AD, Ewald GA, Damiano RJ Jr, Silvestry SC Ann Thorac Surg. 2016 Dec; 102(6)1933-1940. doi: 10.1016/j.athoracsur.2016.05.025.
  • Sequential Photo-oxidative [3 + 2] Cycloaddition/Oxidative Aromatization Reactions for the Synthesis of Pyrrolo[2,1-a]isoquinolines Using Molecular Oxygen as the Terminal Oxidant. Fujiya A, Tanaka M, Yamaguchi E, Tada N, Itoh A J Org Chem. 2016 Aug 19; 81(16)7262-70. doi: 10.1021/acs.joc.6b00439.
  • Complete Coronary Revascularization Improves Survival in Octogenarians. Melby SJ, Saint LL, Balsara K, Itoh A, Lawton JS, Maniar H, Pasque MK, Damiano RJ Jr, Moon MR Ann Thorac Surg. 2016 Aug; 102(2)505-11. doi: 10.1016/j.athoracsur.2016.01.065.
  • Royal Jelly Constituents Increase the Expression of Extracellular Superoxide Dismutase through Histone Acetylation in Monocytic THP-1 Cells. Makino J, Ogasawara R, Kamiya T, Hara H, Mitsugi Y, Yamaguchi E, Itoh A, Adachi T J Nat Prod. 2016 Apr 22; 79(4)1137-43. doi: 10.1021/acs.jnatprod.6b00037.